Nov 4, 2024
According to clinical trials, Gemtesa (vibegron) has an effective half-life of 30.8 hours. The median time to maximum plasma concentration is around 1 to 3 hours. In terms of route of elimination, following a radiolabeled dose, only about 59% of the dose was received in feces and 20% in urine. Total terminal plasma half-life ranges anywhere from 50...
Read MoreOct 31, 2024
Common side effects for the elderly for patients who are on Gemtesa (vibegron) include urinary retention, diarrhea, nausea, constipation, headache, and nasopharyngitis (upper respiratory tract infection). However, based on clinical trials, elderly patients 65 and older have not experienced side effects at a greater rate than younger adults.Key...
Read MoreOct 28, 2024
Metformin is a medication that is often used off-label to treat symptoms of polycystic ovary syndrome (PCOS). Most commonly, metformin is prescribed to women who suffer from polycystic ovary syndrome (PCOS) and are attempting to get pregnant. Metformin can help with a number of symptoms, including menstrual cycles, weight loss, high cholesterol,...
Read MoreOct 21, 2024
Metformin has been known to cause diarrhea in patients. In fact, Diarrhea is a well-known adverse and somewhat common side effect when metformin is initiated for type 2 diabetes. However, it usually resolves itself with continued use (or as your body adapts to your new medication). Only a few cases of chronic diarrhea have been reported after...
Read MoreOct 14, 2024
Metformin is in a class of drugs called biguanides. Metformin helps to control the amount of glucose (sugar) in the blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. It’s commonly prescribed to help with the treatment of Type-2 diabetes. Early research shows metformin reduces the...
Read MoreOct 7, 2024
Metformin is in a class of drugs called biguanides. Metformin helps to control the amount of glucose (sugar) in the blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. It’s commonly prescribed to help with the treatment of Type-2 diabetes.Key TakeawaysImmediate-release and...
Read MoreSep 30, 2024
“Low dose” metformin is usually considered to be 500mg tablets. Most commonly, 500 milligram tablets are prescribed and produced based on the research and evidence of its effectiveness and efficacy at these levels. AJ Garber’s study on metformin concluded, “compared to placebo, 500mg metformin decreased HbA1c 0.6% and 2000...
Read MoreSep 29, 2024
Qulipta (atogepant) trials showed that patients who took Qulipta against patients who took a placebo experienced a 7% decrease in body weight. More patients experience weight decrease when on the 10 mg prescription (3.8%) than on the 30 mg prescription (3.2%). And oddly, only 5.3% of patients on the 60 mg prescription experienced a weight decrease....
Read MoreSep 23, 2024
Qulipta (atogepant) is a prescription drug used daily for the preventive treatment of episodic migraine (with headaches occurring up to 14 days per month) in adults. Its mechanism, which involves blocking calcitonin gene-related peptide (CGRP) receptors, is focused on preventing the onset of migraine attacks. There are no off-label uses or...
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