Buy Zyban Online (Bupropion Hydrochloride)

Introduction

Zyban (bupropion) is a prescription medication used primarily for smoking cessation by reducing nicotine cravings and withdrawal symptoms. It helps individuals gradually quit smoking by altering neurotransmitter activity in the brain. Unlike nicotine replacement therapies, Zyban does not contain nicotine but instead influences dopamine and norepinephrine levels to reduce dependence on cigarettes.

Other Potential Uses:

While primarily used for smoking cessation, bupropion is also prescribed under the brand name Wellbutrin for:

  • Major Depressive Disorder (MDD)

  • Seasonal affective disorder (SAD)

Zyban
150mg Tablet (Sustained-Release)

Prescription required. Can not be split. Product of New Zealand. Shipped from New Zealand.


To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more

Why Prescribed

Zyban is prescribed to individuals who wish to quit smoking but struggle with withdrawal symptoms, such as irritability and strong urges to smoke. By modifying brain chemistry, Zyban can:

  • Reduce the severity of nicotine cravings.

  • Decrease withdrawal symptoms that make quitting difficult.

  • Improve the likelihood of long-term smoking cessation.

Physicians may also suggest combining Zyban with nicotine replacement therapies (NRT) like patches or gum for additional support.

How to Use

Zyban should be taken as prescribed by a healthcare provider to ensure effectiveness and minimize side effects.

Dosage and Administration:

  • Take exactly as directed by your physician. Do not take more than prescribed, as excessive doses can increase the risk of seizures.

  • Initial Dose: 150 mg orally once daily for three days.

  • Maintenance Dose: May be increased to 150 mg twice daily, with at least 8 hours between doses.

  • In some instances, smoking may continue for the first week of treatment. However, a quit date should be set for the second week of Zyban use.

  • If smoking cessation is not achieved within 7 weeks, your physician may re-evaluate the treatment plan.

  • Zyban can be taken with or without food to minimize stomach discomfort.

  • Do not crush, chew, or break tablets; this can interfere with the medication's controlled release.

  • Do not stop Zyban suddenly unless directed by a doctor. Although Zyban is not habit-forming, abrupt discontinuation can lead to withdrawal symptoms due to sudden shifts in neurotransmitter levels.

Missed Dose:

  • If you miss a dose, skip it if your next scheduled dose is soon.

  • Do not take extra medication to make up for a missed dose.

Overdose Management:

  • Overdosing on Zyban can be fatal and may cause severe seizures, hallucinations, irregular heartbeat, shallow breathing, or loss of consciousness.

  • If an overdose is suspected, seek emergency medical attention immediately or call Poison Control at 1-800-222-1222 in the US or 1-844-POISON-X (1-844-764-7669) in Canada.

Side Effects

Like all medications, Zyban may cause side effects. While Zyban is generally well-tolerated, it’s important to be aware of these potential side effects. 

Common Side Effects (Typically Mild to Moderate):

  • Difficulty sleeping

  • Dry mouth

  • Changes in appetite

  • Changes in taste

  • Nausea

  • Rash

  • As your body adjusts to the medication, some side effects may improve. If any effects persist or get worse, talk with your healthcare provider. 

Serious Side Effects (Seek Immediate Medical Attention):

  • Seizures: Zyban lowers the seizure threshold, especially in individuals with risk factors (e.g., history of epilepsy, head trauma, or excessive alcohol use).

  • Severe Mood Changes: Increased anxiety, depression, suicidal thoughts, panic attacks, impulsivity, agitation, hostility, or aggressive behavior.

  • Cardiac Issues: Irregular heartbeats, fast heart rate, or significant blood pressure spikes.

  • Vision Problems: Blurred vision, tunnel vision, eye pain, seeing halos around lights.

  • Allergic Reactions: Symptoms such as hives, swelling of the face/throat, difficulty breathing, or a severe skin rash with blistering require emergency care.

Severe Mental Health Reactions:

  • Smoking cessation itself can cause mood instability. Antidepressants like bupropion (the active ingredient in Zyban) are also associated with suicidal thoughts or actions. This appears to be more prominent in adolescents and young adults. 

  • Patients should be monitored for changes in mood and behavior, particularly in the early weeks of treatment.

  • Zyban may not be appropriate for individuals with a history of bipolar disorder, as it may increase the intensity or frequency of manic episodes. 

If any serious or unusual symptoms occur, contact a healthcare provider immediately.

Warnings and Precautions

Zyban is not suitable for everyone. It carries specific risks and contraindications that must be considered before starting treatment.

Contraindications:

  • Seizure Disorders: Zyban can trigger seizures and should never be used by individuals with epilepsy or a history of seizures.

  • Eating Disorders: Individuals with anorexia nervosa or bulimia have a higher risk of seizures when taking Zyban.

  • Alcohol or Sedative Withdrawal: People who have recently stopped drinking alcohol, benzodiazepines (e.g., Xanax, Valium), or seizure medications should avoid Zyban due to increased seizure risk.

  • Use of MAO Inhibitors: MAOIs (such as phenelzine, tranylcypromine, or selegiline) should not be used within 14 days before or after Zyban, as a dangerous drug interaction could occur.

Precautions for Specific Populations:

  • Pregnancy and Breastfeeding: The effects of Zyban on unborn babies are unclear. Pregnant women should consult a doctor before using this medication.

  • Mental Health Conditions: Patients with a history of bipolar disorder, depression, or anxiety should be closely monitored for mood changes.

  • Heart Disease and Hypertension: Zyban can elevate blood pressure, especially when combined with nicotine patches.

Storage

To maintain Zyban’s effectiveness and ensure safety:

  • Store at room temperature (68°F to 77°F / 20°C to 25°C).

  • Keep away from moisture, heat, and direct sunlight.

  • Do not store in bathrooms due to humidity exposure.

  • Keep out of reach of children.

  • Properly dispose of expired or unused medication as directed by a pharmacist.

Bupropion Information

Bupropion



(byoo proe' pee on)

Aplenzin®
Budeprion® SR¶
Budeprion® XL¶
Buproban®¶
Forfivo® XL
Wellbutrin®
Wellbutrin® SR
Wellbutrin® XL
Zyban®

For people taking bupropion (Wellbutrin) for depression:
A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as bupropion during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. This risk should be considered and compared with the potential benefit in the treatment of depression, in deciding whether a child or teenager should take an antidepressant. Children younger than 18 years of age should not normally take bupropion, but in some cases, a doctor may decide that bupropion is the best medication to treat a child's condition.
No matter what your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal, especially at the beginning of your treatment or any time that your dose is increased or decreased. This risk is higher if you or anyone in your family has or has ever had bipolar disorder or mania or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.
You should know that your mental health may change in unexpected ways when you take bupropion or other antidepressants even if you are an adult over age 24 or if you do not have a mental illness and you are taking bupropion to treat a different type of condition. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.
For all patients taking bupropion:
Your health care provider will want to see you often while you are taking bupropion, especially at the beginning of your treatment. Be sure to keep all appointments or office visits with your doctor.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with bupropion and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can visit the Food and Drug Administration (FDA) website: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm or the manufacturer's website to obtain the Medication Guide.
Talk to your doctor about the risks and benefits of taking bupropion.

Bupropion (Aplenzin, Wellbutrin, Wellbutrin SR, Wellbutrin XL) is used to treat depression. Bupropion (Aplenzin, Wellbutrin XL) is also used to treat seasonal affective disorder (SAD; episodes of depression that occur at the same time each year [usually in the fall and winter but rarely may occur in the spring or summer months]). Bupropion (Zyban) is used to help people stop smoking. Bupropion is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain.

Bupropion comes as a tablet and a sustained-release or extended-release (long-acting) tablet to take by mouth. The regular tablet (Wellbutrin) is usually taken three times a day, with doses at least 6 hours apart, or four times a day, with doses at least 4 hours apart. The sustained-release tablet (Wellbutrin SR, Zyban) is usually taken twice a day, with doses at least 8 hours apart. The extended-release tablet (Aplenzin, Wellbutrin XL) is usually taken once daily in the morning; doses of the extended-release tablet should be taken at least 24 hours apart. When bupropion is used to treat seasonal affective disorder, it is usually taken once a day in the morning beginning in the early fall, continuing through the winter, and stopping in the early spring. Sometimes a lower dose of bupropion is taken for 2 weeks before the medication is stopped. Take bupropion with food if the medication upsets your stomach. If you have trouble falling asleep or staying asleep, do not take bupropion too close to bedtime. Take bupropion at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take bupropion exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the sustained-release and extended-release tablets whole; do not split, chew, or crush them.
Your doctor will probably start you on a low dose of bupropion and gradually increase your dose.
It may take 4 weeks or longer before you feel the full benefit of bupropion. Continue to take bupropion even if you feel well. Do not stop taking bupropion without talking to your doctor. Your doctor may decrease your dose gradually.

Before taking bupropion,

tell your doctor and pharmacist if you are allergic to bupropion, any other medications, or any of the ingredients in bupropion tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

tell your doctor if you are taking a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking an MAO inhibitor within the past 14 days. Your doctor will probably tell you not to take bupropion.

do not take more than one product containing bupropion at a time. You could receive too much medication and experience severe side effects.

tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amantadine (Symmetrel); beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); cimetidine (Tagamet); clopidogrel (Plavix); cyclophosphamide (Cytoxan, Neosar); efavirenz (Sustiva, in Atripla); insulin or oral medications for diabetes; medications for irregular heartbeat such as flecainide (Tambocor) and propafenone (Rythmol); medications for mental illness such as haloperidol (Haldol), risperidone (Risperdal), and thioridazine (Mellaril); medications for seizures such as carbamazepine (Tegretol), phenobarbital (Luminal, Solfoton), and phenytoin (Dilantin); levodopa (Sinemet, Larodopa); lopinavir and ritonavir (Kaletra); nelfinavir (Viracept); nicotine patch; oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); orphenadrine (Norflex); other antidepressants such as citalopram (Celexa), desipramine (Norpramin), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), paroxetine (Paxil) and sertraline (Zoloft); ritonavir (Norvir); sedatives; sleeping pills; tamoxifen (Nolvadex, Soltamox); theophylline (Theobid, Theo-Dur, others); thiotepa; and ticlopidine (Ticlid). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

tell your doctor if you have or have ever had seizures, anorexia nervosa (an eating disorder) or bulimia (an eating disorder). Also tell your doctor if you drink large amounts of alcohol but expect to suddenly stop drinking or you take sedatives but expect to suddenly stop taking them. Your doctor will probably tell you not to take bupropion.

tell your doctor if you drink large amounts of alcohol, use street drugs, or overuse prescription medications and if you have ever had a heart attack; a head injury; a tumor in your brain or spine; high blood pressure; diabetes; or liver, kidney, or heart disease.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking bupropion, call your doctor.

you should know that bupropion may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

talk to your doctor about the safe use of alcoholic beverages while you are taking bupropion. Alcohol can make the side effects from bupropion worse.

you should know that bupropion may cause an increase in your blood pressure. Your doctor may check your blood pressure before starting treatment and regularly while you are taking this medication, especially if you also are using nicotine replacement therapy.

you should know that bupropion may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision). Talk to your doctor about having an eye examination before you start taking this medication. If you have nausea, eye pain, changes in vision, such as seeing colored rings around lights, and swelling or redness in or around the eye, call your doctor or get emergency medical treatment right away.

you should know that some people have reported symptoms such as changes in behavior, hostility, agitation, depressed mood, and suicidal thoughts (thinking about harming or killing oneself or planning or trying to do so) while taking bupropion to stop smoking. The role of bupropion in causing these mood changes is unclear since people who quit smoking with or without medication may experience changes in their mental health due to nicotine withdrawal. However, some of these symptoms occurred in people who were taking bupropion and continued to smoke. Some people had these symptoms when they began taking bupropion, and others developed them after several weeks of treatment or after stopping bupropion. These symptoms have occurred in people without a history of mental illness and have worsened in people who already had a mental illness. Tell your doctor if you have or have ever had depression, bipolar disorder (mood that changes from depressed to abnormally excited), schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions), or other mental illnesses. If you experience any of the following symptoms, stop taking bupropion (Zyban) and call your doctor immediately: suicidal thoughts or actions; new or worsening depression, anxiety, or panic attacks; agitation; restlessness; angry or violent behavior; acting dangerously; mania (frenzied, abnormally excited or irritated mood); abnormal thoughts or sensations; hallucinations (seeing things or hearing voices that do not exist); feeling that people are against you; feeling confused; or any other sudden or unusual changes in behavior. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own. Your doctor will monitor you closely until your symptoms get better.

Unless your doctor tells you otherwise, continue your normal diet.

Skip the missed dose and continue your regular dosing schedule. Always allow the full scheduled amount of time to pass between doses of bupropion. Do not take a double dose to make up for a missed one.

Bupropion may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:



drowsiness

anxiety

excitement

difficulty falling asleep or staying asleep

dry mouth

dizziness

headache

nausea

vomiting

stomach pain

uncontrollable shaking of a part of the body

loss of appetite

weight loss

constipation

excessive sweating

ringing in the ears

changes in your sense of taste

frequent urination

sore throat

Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS sections, call your doctor immediately or get emergency medical treatment:



seizures

confusion

hallucinating (seeing things or hearing voices that do not exist)

irrational fears

muscle or joint pain

rapid, pounding, or irregular heartbeat
If you experience any of the following symptoms, stop taking bupropion and call your doctor immediately or get emergency medical treatment:



fever

rash or blisters

itching

hives

swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

hoarseness

difficulty breathing or swallowing

chest pain
Bupropion may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.  However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community.  See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Keep all appointments with your doctor.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking bupropion.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
If you are taking the extended-release tablet, you may notice something that looks like a tablet in your stool. This is just the empty tablet shell and does not mean that you did not get your complete dose of medication.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
¶ This branded product is no longer on the market. Generic alternatives may be available.

The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.