Buy Kayexalate (Sodium Polystyrene Sulfonate) Online (Sodium Polystyrene Sulfonate)

Introduction

Sodium polystyrene sulfonate (SPS), commonly marketed under the brand name Kayexalate, is used to treat hyperkalemia (elevated potassium levels in the blood). It is available in several formulations:

The typical dosing frequency ranges from one to four times daily, depending on the healthcare provider's instructions. Common side effects include gastrointestinal issues such as nausea, vomiting, constipation, or diarrhea, as well as reduced appetite. Always follow your provider's guidance for proper use, as these instructions are guided specifically by individual needs.

Kayexalate
1mEq/g Powder

Prescription required. Product of Canada. Shipped from Canada.


To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more

How to Use

Sodium polystyrene sulfonate (SPS) (or Kayexalate) comes in two forms:

  • Powder: Contains 3.5 grams per level teaspoon for reconstitution into a suspension.

  • Liquid Suspension: Comes in a 15 g per 60 mL bottle.

Although the powder form requires mixing before use, both forms can deliver the same dosages. Your dose depends on your potassium levels, how well you're responding to the medication, and whether you experience any side effects.

Adults:

  • Oral: The typical dose is 15 grams, taken 1 to 4 times daily.

  • Rectal (Enema): The typical dose is 30 to 50 grams, inserted into the rectum every 6 hours.

Children:

A doctor will determine if SPS (or Kayexalate) is safe for your child and calculate the correct dose based on their blood potassium levels.

Sodium polystyrene sulfonate (SPS) (or Kayexalate) can interact with certain medications or supplements. Always inform your doctor and pharmacist about all your medications or supplements, including over-the-counter products, vitamins, and herbal supplements. Below are some important interactions:

Medications That May Alter or be Altered by  Kayexalate Therapy (May Require Dose Adjustment):

  • Antacids

  • Magnesium hydroxide

  • Digoxin

  • Sorbitol

  • Lithium

  • Thyroxine

Your doctor may adjust doses or monitor you closely if you take any of these medications with Kayexalate. Always follow your healthcare provider's advice.

Side Effects

Some side effects may improve as your body adjusts to the medication. Contact your healthcare provider immediately if these symptoms persist or worsen over time.

Common Side Effects:

  • Low appetite

  • Nausea

  • Vomiting

  • Constipation

  • Diarrhea

Other Side Effects:

  • Gut irritation

  • Blockage in the gut (fecal impaction)

The risk of developing a gut blockage may increase when administered rectally (i.e., enema). Following the dosage guidelines provided by your doctor is essential. Kayexalate is associated with electrolyte disturbances, and taking more than recommended increases this risk. Electrolyte disturbances can manifest in many ways, ranging from fluid retention (e.g., swelling around feet and ankles) to more serious effects, including irregular heart rhythm or seizures. 

Serious Side Effects:

Get medical help right away if you experience any of the following:

  • Intestinal necrosis (low blood flow to the stomach and intestines), characterized by:

    • Bleeding in stool

    • Nausea, vomiting, constipation, or diarrhea

    • Fever

    • Stomach pain

  • Low electrolyte levels, characterized by:

    • Muscle cramps or pain

    • Numbness or tingling

    • Weakness or fatigue

    • Shortness of breath

    • Confusion

Overdose Symptoms:

Overdosage can lead to dangerous electrolyte disturbances, including low blood potassium, calcium, and magnesium levels. These disturbances have the potential to be life-threatening. Get emergency help immediately if you notice any of the following signs of an overdose:

  • Dizziness or lightheadedness

  • Drowsiness or fainting

  • Fast, slow, or irregular heartbeat

  • Muscle spasms or twitching

  • Trembling or pounding pulse

Sodium Polystyrene Sulfonate Information

Sodium Polystyrene Sulfonate



(pol ee stye' reen)

Kalexate®
Kayexalate®
Kionex®
SPS®

Sodium polystyrene sulfonate is used to treat hyperkalemia (increased amounts of potassium in the body). Sodium polystyrene sulfonate is in a class of medications called potassium-removing agents. It works by removing excess potassium from the body.

Sodium polystyrene sulfonate comes as a suspension and as an oral powder for suspension to take by mouth. The suspension may also be given rectally as an enema. Sodium polystyrene sulfonate is usually taken or used one to four times a day. Take or use sodium polystyrene sulfonate at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take or use sodium polystyrene sulfonate exactly as directed. Do not take or use more or less of it or take or use it more often than prescribed by your doctor.
Shake the suspension well before each use to mix the medication evenly.
If you are taking sodium polystyrene sulfonate powder by mouth, mix the powder with 20 to 100 mL (about 1 to 3 ounces) of water or syrup as directed by your doctor. Measure carefully, using level teaspoonfuls of the powder. Use the mixture shortly after preparation; do not store beyond 24 hours.
Do not heat sodium polystyrene sulfonate suspension or add it to heated foods or liquids.
If you are receiving sodium polystyrene sulfonate as an enema, you will probably be given a cleansing enema before and after you receive this medication. Hold the sodium polystyrene sulfonate enema contents as long as possible, up to several hours.
Do not use sorbitol along with sodium polystyrene sulfonate products. Serious problems have been reported when sorbitol was used with sodium polystyrene sulfonate.

Before taking or receiving sodium polystyrene sulfonate,

tell your doctor and pharmacist if you are allergic to sodium polystyrene sulfonate, other polystyrene sulfonate resins, any other medications, or any of the ingredients in sodium polystyrene sulfonate products. Ask your pharmacist for a list of the ingredients.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antacids, antibiotics taken by mouth; anticoagulants such as warfarin (Coumadin, Jantoven); digoxin (Lanoxin); laxatives; lithium (Lithobid); or thyroxine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. If you are taking any other medications by mouth, take them at least 3 hours before or 3 hours before or after taking sodium polystyrene sulfonate.

tell your doctor if you have low levels of potassium in your blood, a blockage in your intestine or colon, or if you have recently had surgery and your bowel function has not returned to normal. Your doctor will probably tell you not to take sodium polystyrene sulfonate. Newborn infants should not receive sodium polystyrene sulfonate.

tell your doctor if you have or have ever had constipation; surgery to remove all or part of your large bowel or surgery for other intestinal problems; inflammatory bowel disease, ischemic colitis (decreased blood flow to the bowels), gastroparesis (slowed movement of food from the stomach to the small intestine) or other bowel problems; heart failure; high blood pressure; edema (fluid retention; excess fluid held in body tissues); or kidney disease.

tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking sodium polystyrene sulfonate, call your doctor.

tell your doctor if you are on a sodium-restricted diet.

Talk to your doctor before using salt substitutes containing potassium or foods that are high in potassium.

Take or use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take or use a double dose to make up for a missed one.

Sodium polystyrene sulfonate may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:



diarrhea

nausea

vomiting

loss of appetite

Some side effects can be serious. If you experience any of these symptoms, stop taking or using sodium polystyrene sulfonate and call your doctor immediately:



constipation

seizures

unusual bleeding

confusion

muscle weakness

abdominal pain

fast, pounding, or irregular heartbeat
Sodium polystyrene sulfonate may cause other side effects. Call your doctor if you have any unusual problems while taking or using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature (unless told otherwise by your pharmacist) and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.  However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community.  See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to sodium polystyrene sulfonate.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.