Zithromax (azithromycin) is an antibiotic used to treat various bacterial infections, including respiratory, skin, ear, and sexually transmitted infections. It belongs to a class of drugs called macrolide antibiotics, which work by stopping the growth of certain strains of bacteria.
While Zithromax (azithromycin) is also available in an injectable form, it’s typically taken orally as a tablet or liquid suspension when used at home. It’s important to take the medication exactly as prescribed by your healthcare provider. If you have difficulty swallowing tablets, you may discuss with your provider about switching to the liquid form.
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The most common side effects of Zithromax (azithromycin) include gastrointestinal issues like diarrhea, nausea, and stomach pain. Contact your healthcare provider if any side effects become severe or do not go away.
Common side effects include:
Diarrhea (up to 5%)
Nausea (up to 3%)
Other less common side effects include:
Vomiting
Abdominal pain
Headache
Zithromax (azithromycin) has been associated with severe allergic reactions in rare cases. If you develop a rash, swelling around the neck or face, or difficulty breathing, seek medical attention right away.
Antibiotics, including azithromycin, can increase the risk of diarrhea caused by Clostridioides difficile, or C. diff. These infections can sometimes become severe. It’s important to follow up with your healthcare provider if diarrhea occurs or persists after you finish taking azithromycin.
Azithromycin has been associated with prolonging the QT interval. The QT interval is an important electrocardiogram (ECG) component that helps detect potential heart problems, such as arrhythmias (heart beating out of rhythm). Certain heart conditions and medications can also impact the QT interval and can increase the risk of dangerous arrhythmias if used together with azithromycin. Talking with your healthcare providers about your medical history and any other medications you use is critical.
Zithromax (azithromycin) is often prescribed as a five-day course, with 500 mg taken on the first day followed by 250 mg taken once daily for the next four days (often referred to as a ‘Z-pak’). However, in some instances, it may be recommended for a longer period or intermittently over time. For some conditions, Zithromax (azithromycin) may also be given as a single large dose, such as 1 gram taken at once for certain types of infections like chlamydia.
The recommended dosage varies depending on individual needs and the infection being treated, so following your healthcare provider's instructions is important.
Common questions and answers about Zithromax (azithromycin):
For some infections, Zithromax (azithromycin) starts working within a few days of starting treatment, though you may begin to feel better within the first 24-48 hours. It's essential to finish the entire course of medication, even if symptoms improve early, to ensure the infection is fully treated.
Zithromax (azithromycin) can be taken with or without food. However, if it causes stomach upset, you may find it easier to take it with food. Be sure to follow your healthcare provider's recommendations on how to take your dose.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.